Maximizing the precision in estimating parameters in a quantum system subject to instrumentation constraints is cast as a convex optimization problem. We account for prior knowledge about the parameter range by developing a worst-case and average case objective for optimizing the precision. Focusing on the single parameter case, we show that the optimization problems are linear programs. For the average case the solution to the linear program can be expressed analytically and involves a simple search: finding the largest element in a list. An example is presented which compares what is possible under constraints against the ideal with no constraints, the Quantum Fisher Information.